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Communicable disease threats report, 13-19 December 2025, week 51

This issue of the ECDC Communicable Disease Threats Report (CDTR) covers the period 13-19 December 2025 and includes updates on respiratory virus epidemiology, SARS-CoV-2 variants, mpox, leprosy, Marburg virus disease, dengue, and chikungunya.

Multi-model analysis to quantify the impact of vaccination on COVID-19 and influenza hospitalisation burden among older adults in the EU/EEA, 2024/25

Influenza vaccine coverage remains below the WHO-recommended threshold for risk groups in most EU/EEA countries, while COVID-19 vaccine coverage is declining across most countries.

Preparedness of public health laboratories for respiratory infectious diseases – EU/EEA country perspectives on lessons learned from the COVID-19 pandemic

The purpose of this study was to provide evidence on how to help public health laboratories be better prepared and more resilient to future public health challenges related to respiratory infectious diseases.

From crisis to preparedness: Lessons for Europe’s public health laboratories

A study published today shows how public health laboratories can become more resilient against future respiratory infectious diseases. The findings call for sustained capacity, better coordination and EU-level support.

New analysis indicates that vaccines greatly reduce hospitalisations for flu and COVID-19

A new modelling study from RespiCompass, the European respiratory disease modelling hub coordinated by ECDC, indicates that influenza and COVID-19 vaccination programmes markedly reduced hospitalisations among older adults across Europe in the 2024/25 season.

Weekly respiratory virus update, week 49, November 2025

Respiratory viruses are on the rise across the EU/EEA: influenza activity is increasing rapidly and circulating widely, RSV is slowly increasing, while SARS-CoV-2 circulation continues to decrease.

Communicable disease threats report, 6-12 December 2025, week 50

This issue of the ECDC Communicable Disease Threats Report (CDTR) covers the period 6-12 December 2025 and includes updates on respiratory virus epidemiology in the EU/EEA, measles, Middle East respiratory syndrome (MERS-CoV), West Nile virus, and Marburg virus disease (MVD).

Protocol to measure COVID-19 XBB.1.5 vaccine effectiveness in the immunocompromised population during the 2023 autumn vaccination campaign

This protocol describes the methods to estimate the Coronavirus disease 2019 (COVID-19) XBB.1.5. monovalent-adapted VE in immunocompromised persons (ICP), against COVID-19 hospitalisations and deaths.

External quality assessment of European SARS-CoV-2 and zoonotic influenza Bioinformatics (ESIB-EQA), 2024

SARS-CoV-2 and influenza viruses are significant public health threats with varying impacts on global health. SARS-CoV-2, the virus behind the COVID-19 pandemic, exhibits high transmissibility and recurrent waves driven by new variants.

Communicable disease threats report, 29 November – 5 December 2025, week 49

This issue of the ECDC Communicable Disease Threats Report (CDTR) covers the period 22 – 28 November 2025 and includes updates on respiratory virus epidemiology in the EU/EEA, chikungunya, West Nile virus, Marburg virus disease, Influenza A(H5N2), HIV/AIDS surveillance, Ebola, Middle East Respiratory virus (MERS), shigellosis Cabo Verde.

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