The ECDC Communicable Disease Threats Report (CDTR) is a weekly bulletin for epidemiologists and health professionals on active public health threats. This issue covers the period 2-8 October 2022 and includes updates on avian influenza, COVID-19, dengue, Ebola, invasive meningococcal disease, West Nile Virus, MERS-CoV, monkeypox, and hepatitis.