This issue of the ECDC Communicable Disease Threats Report (CDTR) covers the period 27 November – 3 December 2022 and includes updates on COVID-19, Ebola, diphtheria, respiratory syncytial virus, seasonal influenza, monkeypox, mass gathering monitoring at the FIFA World Cup 2022 Qatar, Chikungunya, dengue, Shigella sonnei, poliomyelitis, meningitis, cholera.